Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions

نویسندگان

  • Petri A Turhanen
  • Jouko J Vepsäläinen
چکیده

Unexpected degradation of the P-C-P bridge from novel bisphosphonate derivative 1a and known etidronate trimethyl ester (1b) has been observed under mild reaction conditions. A proposed reaction mechanism for the unexpected degradation of 1a and 1b is also reported.

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عنوان ژورنال:
  • Beilstein Journal of Organic Chemistry

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2008